Sodium–Glucose Co-transporter 2 Inhibitors in Heart Failure: Recent Data and Implications for Practice

Cardiovascular (CV) disease remains a leading cause of morbidity and mortality worldwide with heart failure increasing in prevalence. Despite the significant advances in therapies and prevention, mortality and morbidity are still high and quality of life poor. The opportunity for CV disease prevention in patients with T2DM has recently expanded with antihyperglycemic agents demonstrating significant reductions in the risk of major adverse cardiovascular events (MACE) including many trials with SGLT2 inhibitors showing that drugs in this class cause robust reductions in heart failure. Although the exact mechanisms of CV benefit remain uncertain, they appear to be unrelated to the direct glucose-lowering effects.  These agents have triggered a shift beyond glucose control, to a broader strategy of comprehensive CV risk reduction.   

This comprehensive review article aims to educate practicing cardiologists and related healthcare professionals of the latest developments in this field, and support better patient outcomes.

Radcliffe Education requires contributors to our CME programmes to disclose any relevant financial relationships that have occurred within the past 12 months that could create a conflict of interest. These will be identified in the faculty section if applicable.

This review article, 'Sodium-Glucose Co-transporter 2 Inhibitors in Heart Failure: Recent Data and Implications for Practice' is accredited by the European Board for Accreditation in Cardiology (EBAC) for 1 hour of external CME credits.

Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS).

Through an agreement between the European Board for Accreditation in Cardiology and the American Medical Association, physicians may convert EBAC External CME credits to AMA PRA Category 1 Credits™. Information on the process to convert EBAC credit to AMA credit can be found on the AMA website.

There is no fee for taking part in this online learning activity.

Activities are designed to be completed within 60 minutes and must be completed by the registered user. Physicians should only claim credits for time spent on the activity. To successfully earn credit, participants must complete the activity in full in the indicated time frame.

To complete the course and claim certification participants must:

• Read the PDF of the review article carefully and thoroughly, consider the learning objectives and implications, and then complete post-test questions at the end of the activity. Users must read and study the activity in its entirety before completing the post-test questions.
• Your results will be automatically saved and if the required pass score is achieved, you will be eligible to claim credit for the activity and receive a certificate of completion.