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THIS CONTENT IS FOR HEALTHCARE PROFESSIONALS ONLY

Heart Failure Management Hub

This Heart Failure Management Hub provides a range of valuable educational assets to facilitate the use of SGLT-2 inhibitors and other guideline directed medical therapies as foundational treatment for heart failure (HF).

Supported by an unrestricted educational grant from AstraZeneca.

Discover our Videos and documents

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Discussions

(27 contents)

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Discussions

QoL and Functional Measures of Treatment Success

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author

Shelley Zieroth, Mikhail Kosiborod

Dr Kosiborod and Dr Zieroth discuss QoL and functional status as tangible measurements of treatment success.

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Discussions

Clinical Evidence

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Shelley Zieroth, Mikhail Kosiborod

Dr Kosiborod and Dr Zieroth look at the relationship between initiating GDMT and QoL / functional status improvement. They discuss some of the specific clinical trial data showing how initiating SGLT-2 inhibitors improves QoL and functional outcomes.

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Discussions

Practically Implementing PROMs

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Shelley Zieroth, Mikhail Kosiborod

In this final part of this series, Dr Kosiborod and Dr Zieroth discuss practical implication of these patient reported outcome measures (PROMs).

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Discussions

Initiating SGLT-2 Inhibitors

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author

Biykem Bozkurt, Giuseppe Rosano

Prof Rosano and Dr Bozkurt examine recent guidelines and consider best practice for initiating SGLT-2 inhibitors across the continuum of HF and in patients already on HF medication versus those who are treatment-naïve.

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Discussions

Evolving the Management Approach - AEs and MDTs

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Biykem Bozkurt, Giuseppe Rosano

Prof Rosano and Dr Bozkurt discuss the practicalities of continual management of HF patients on an SGLT-2 inhibitor and how the broader multidisciplinary team should be aware of the benefits of early SGLT-2 initiation in HF.

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Discussions

What is GDMT?

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Andrew JS Coats, Mikhail Kosiborod

Prof Coats and Dr Kosiborod summarise foundational guideline-directed medical therapy (GDMT) across the spectrum of heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).

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Discussions

Early Initiation and Better Clinical Outcomes

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Andrew JS Coats, Mikhail Kosiborod

Prof Coats and Dr Kosiborod discuss the relationship between early initiation of foundational GDMT and better clinical outcomes by exploring recent clinical trial data from STRONG-HF.

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Discussions

Achieving Early Uptake of GDMT

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author

Andrew JS Coats, Mikhail Kosiborod

In this final part, Prof Coats and Dr Kosiborod cover practical approaches for ensuring early optimal GDMT in heart failure, such as, the use of electronic health records and protocols for specific patient subgroups.

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Discussions

The DELIVER Trial in Brief

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Carolyn Lam, John JV McMurray

Prof Lam discusses DELIVER with one of the trial’s lead investigators, Prof McMurray. As well as the key results from DELIVER, they consider how to apply them to HFpEF patients in the real-world.

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Discussions

DELIVER and DAPA-HF Pooled Analysis in Brief

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Carolyn Lam, John JV McMurray

Prof Lam and Prof McMurray put into context the pooled analysis of DELIVER and DAPA-HF and consider whether these results can be extrapolated to the entire HF population, addressing the suitability of patients according to their individual EF.

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Discussions

Implementation Strategies for GDMT in Respect of the New Guidelines

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Mikhail Kosiborod, Harriette Van Spall

In this short interview, Dr Kosiborod and Dr Van Spall summarise some of the key changes in guidance following the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

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Discussions

The PRESERVED-HF Study: Effects of Dapagliflozin

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author

Mikhail Kosiborod

In this short presentation on behalf of the investigators, Dr Kosiborod summarises the PRESERVED-HF study, looking at effects of Dapagliflozin on symptoms and functional status in patients with HF and preserved EF.

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Discussions

Effects of Dapagliflozin in Patients With Chronic Kidney Disease

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author

John JV McMurray

In this presentation of the ESC 2021 poster, 'Effects of Dapagliflozin in Patients With Chronic Kidney Disease, With and Without Heart Failure', Prof McMurray provides a comprehensive overview of the study's background, methods and results.

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Discussions

Cardio-renal Pathophysiology

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Kamlesh Khunti, Shelley Zieroth

Prof Khunti outlines what clinicians need to know about the relationship between chronic kidney disease and cardiovascular disease. Prof Heerspink addresses why clinicians should be encouraged to intervene early for patients living with CKD.

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Discussions

Screening for CKD

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Kamlesh Khunti, Shelley Zieroth

Prof Khunti addresses the burden of CKD globally, including the prevalence of CKD in patients with type 2 diabetes. The faculty discuss existing tools for screening for CKD, and the recommendations of international guidelines.

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Discussions

Treatment Options in CKD

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Shelley Zieroth, Kamlesh Khunti

Dr Zieroth enquires of the latest treatment options for CKD, with Prof Heerspink advising on evidence supporting the use of treatments, whilst Prof Khunti provides insight to the role of initiating SGLT2 therapy, and underlines the urgency to treat.

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Discussions

Where Do SGLT-2 Inhibitors Fit Into the New Guidelines for HFrEF?

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author

Giuseppe Rosano, Andrew JS Coats

Following the release at ESC 2021 of updated guidelines for the diagnosis and treatment of acute and chronic heart failure, Prof Coats and Prof Rosano address key considerations of where SGLT-2 inhibitors fit into the new guidelines for HFrEF.

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Discussions

When and How to Initiate SGLT-2 Inhibitors in HFrEF

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author

Andrew JS Coats, Giuseppe Rosano

Following the release at ESC 2021 of updated guidelines for the diagnosis and treatment of acute and chronic heart failure, Prof Coats and Prof Rosano provide a comprehensive update on when and how to initiate SGLT-2 inhibitors.

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Discussions

Choosing an SGLT-2 Inhibitor – Making an Evidence-based Choice

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author

Andrew JS Coats, Giuseppe Rosano

Following the release at ESC 2021 of updated guidelines for the diagnosis and treatment of acute and chronic heart failure, Prof Coats and Prof Rosano discuss how to make evidence-based choices in the selection of SGLT-2 inhibitors.

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Discussions

Optimising Treatment of HF

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author

Martin R Cowie

In part one of this programme 'Optimising Treatment of HF', Prof Cowie introduces the topic and reviews the learning objectives.

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Discussions

A Review of Recent SGLT2 Inhibitor Data

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author

Giuseppe Rosano

In part two of 'Optimising Treatment of HF', Prof Rosano reviews recent SGLT2 trial data, including DAPA – HF, and Emperor Reduced.

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Discussions

New HFrEF: When and How Should We Initiate an SGLT2 Inhibitor?

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author

Javed Butler

In part three of 'Optimising Treatment of HF', Dr Butler presents a case, and considers available treatment strategies and the optimal approach for HFrEF medications.

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Discussions

Existing HF-REF: Augmenting the SOC

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Shelley Zieroth

In part four of 'Optimising Treatment of HF', Dr Zieroth reviews how guideline-directed medical therapy for HFrEF has evolved, and notes that further changes are coming to practice.

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Discussions

How Will SGLT2 Inhibition Provide the Greatest Impact on HF-REF?

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Martin R Cowie, Javed Butler, Shelley Zieroth, Giuseppe Rosano

In the final part of this programme 'Optimising Treatment of HF', Prof Cowie moderates a discussion with the faculty.

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Discussions

Guideline Directed Medical Therapy in HF

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author

Giuseppe Rosano, Biykem Bozkurt

In this short peer-to-peer discussion, Dr Biykem Bozkurt, and Prof Giuseppe Rosano, discuss the main updates from the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

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Discussions

SGLT-2 Inhibitors Across the Range Of EF

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author

Giuseppe Rosano, Mikhail Kosiborod

In this short peer-to-peer discussion, Prof Giuseppe Rosano and Dr Mikhail Kosiborod, discuss the main updates from the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

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Discussions

Using Guideline Directed Medical Therapy to Improve Outcomes

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author

Mikhail Kosiborod, Giuseppe Rosano

In this short peer-to-peer discussion, Prof Giuseppe Rosano and Dr Mikhail Kosiborod, discuss the main updates from the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

Heart Failure in Focus Podcast

(6 contents)

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Episode 6: Cardiorenal Care in Practice
20:40

Podcasts

Episode 6: Cardiorenal Care in Practice

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author

Muthiah Vaduganathan

Dr Muthiah Vaduganathan speaks with Dr Kieran McCafferty, Consultant Nephrologist at Barts NHS Health Trust London, about the growing need for effective management strategies in cardiorenal disease.

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Episode 5
23:06

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Episode 5: Functional & QoL Outcomes in a Sea of Clinical Event Data

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Muthiah Vaduganathan, Mikhail Kosiborod

Dr Vaduganathan is joined by Dr Mikhail Kosiborod, leading expert on Quality of Life (QoL) instruments world-wide, to discuss functional and QoL outcomes of foundational therapies in Heart Failure (HF) and the clinical application of this data.

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Episode 4: Mitigating Clinical Inertia in Heart Failure

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Muthiah Vaduganathan, Tariq Ahmad

Dr Vaduganathan is joined by Dr Tariq Ahmad to discuss the reality of sub-optimal treatment and possible ways forward using behavioural “nudges” embedded within electronic health records.

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21:04

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Episode 3: 4 Onboard: Implementing GDMT

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Muthiah Vaduganathan, Biykem Bozkurt

Dr Vaduganathan is joined by Dr Biykem Bozkurt, for the third episode, to discuss some of the most challenging questions around implementing guideline directed medical therapy (GDMT).

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Episode 2: Your Questions Answered
20:17

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Episode 2: Your Questions Answered

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Muthiah Vaduganathan, Carolyn Lam

Dr Vaduganathan is joined by Prof Carolyn Lam to continue the theme of SGLT-2 inhibitors in heart failure. Listen to them answer your questions about SGLT-2 inhibitors and the practical management of heart failure patients.

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Episode 1: Emerging Data from the ESC
20:07

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Episode 1: Emerging Data from the ESC

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author

Muthiah Vaduganathan, Scott Solomon

Dr Muthiah Vaduganathan is joined by Prof Scott Solomon for the first episode in this new series, Heart Failure in Focus, to discuss the DELIVER data which was released at the ESC Congress 2022 in Barcelona.

CME Courses

(2 contents)

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CME Courses

Incorporating GDMT and PRO Endpoints for Personalised Heart Failure Management

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Andrew JS Coats, Mikhail Kosiborod, Shelley Zieroth, Biykem Bozkurt, Giuseppe Rosano

Published: 23/03/2023

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CME Courses

SGLT-2 Inhibitors - Another Piece of the Puzzle in Heart Failure

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Scott Solomon, John JV McMurray, Carolyn Lam, Muthiah Vaduganathan

Published: 08/09/2022

Symposia

(7 contents)

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Symposia

SGLT2 Inhibitors: Light at the End of the Tunnel

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author

Scott Solomon

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice. 

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Symposia

SGLT2 Inhibitors Across the Spectrum of Heart Failure

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author

John JV McMurray

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice. 

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Symposia

Practical Considerations for Treating HF With Mildly Reduced and Preserved EP

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author

Carolyn Lam

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice. 

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Symposia

Implementing Best Practices Across the Spectrum of Heart Failure

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author

Muthiah Vaduganathan

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice. 

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Symposia

The ACC Heart Failure Guidelines 2022: What Did We Learn?

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Biykem Bozkurt

This symposium, part of Heart Failure Online 2022, provides a succinct overview of the ACC heart failure guideline updates.

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Symposia

The Future of Guidelines: Towards Personalised Care?

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author

Mikhail Kosiborod

This symposium, part of Heart Failure Online 2022, provides a succinct overview of the ACC heart failure guideline updates.

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Symposia

HFpEF: The Final Chapter in the Heart Failure Story?

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Andrew JS Coats

This symposium, part of Heart Failure Online 2022, provides a succinct overview of the ACC heart failure guideline updates.

Roundtables

(3 contents)

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Roundtables

Ejection Fraction - How Important Is It Today?

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author

Martin R Cowie, Richard Hobbs, Kieran Docherty, Bharathi Upadhya

During the first part of this roundtable, chaired by Prof Cowie, our multidisciplinary panel discuss the importance of EF, and analyse survey data.

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Roundtables

HFrEF and HFpEF Case Review

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Martin R Cowie, Richard Hobbs, Kieran Docherty, Bharathi Upadhya

During the second part of this roundtable, our multidisciplinary panel discuss two patient cases and their treatment strategies based on recent guidelines and data updates.

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Roundtables

The Expanding Role of Primary Care in Ongoing HF Management

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Richard Hobbs, Martin R Cowie, Kieran Docherty, Bharathi Upadhya

During the final part of this roundtable, the panel discuss the role of primary care in ongoing heart failure management.