Roxana Mehran

Roxana Mehran is an internationally recognised interventional cardiologist and clinical researcher based in New York, United States. She has spent much of her professional career at the Icahn School of Medicine at Mount Sinai and Mount Sinai Hospital, where she has become a leading figure in cardiovascular clinical trials, interventional cardiology, and outcomes research. Her work is widely noted for its focus on improving patient outcomes, advancing evidence-based care, and promoting sex-specific research in cardiovascular medicine.

Academic History

Professor Mehran pursued her medical education and postgraduate training in internal medicine and cardiology, followed by subspecialty training in interventional cardiology. Her academic career has been closely aligned with Mount Sinai, where she has advanced through senior academic ranks.

She currently holds appointments as Professor of Medicine (Cardiology) and Professor of Population Health Science and Policy at the Icahn School of Medicine at Mount Sinai. Her academic work integrates clinical medicine, population health, and rigorous clinical trial methodology, reflecting her commitment to translating research findings into real-world cardiovascular care.

Career Overview

Professor Mehran serves as Director of Interventional Cardiovascular Research and Clinical Trials at The Zena and Michael A. Weiner Cardiovascular Institute at Mount Sinai Hospital. In this role, she has led the development of a globally respected data and clinical coordination centre that supports large, multicentre, multinational cardiovascular clinical trials. Under her leadership, this centre has become a major contributor to studies aimed at improving outcomes and quality of life for patients undergoing interventional cardiovascular procedures.

Her research has had a particular emphasis on antithrombotic therapy, including anticoagulation and antiplatelet regimens following angioplasty and transcatheter valve replacement. In parallel, she has been a prominent advocate for the collection, analysis, and interpretation of sex-specific data in cardiovascular clinical trials, helping to address longstanding gaps in evidence for women with cardiovascular disease.

Professor Mehran has played a significant role in cardiovascular publishing and professional leadership. She serves on the editorial boards of multiple leading peer-reviewed journals, including the Journal of the American College of Cardiology, Circulation, and Circulation Research. She is also a member of the editorial board of Interventional Cardiology: Reviews, Research, Resources.

In addition to her editorial work, she holds numerous leadership positions within major professional organisations. She serves on the board of trustees of the Society of Cardiac Angiography and Interventions, is a member of the Program Committee for the American Heart Association Scientific Sessions, and sits on the board of directors for Harboring Hearts. She is also Program Chair for the Society of Cardiac Angiography and Interventions’ Women in Innovations Initiative. Beyond these roles, she serves as Chief Scientific Officer of the Clinical Trials Center at the Cardiovascular Research Foundation.

Career Timeline

• Completion of medical education and postgraduate training in cardiology and interventional cardiology
• Appointment to faculty positions at the Icahn School of Medicine at Mount Sinai
• Named Professor of Medicine (Cardiology) and Professor of Population Health Science and Policy, Mount Sinai
• Appointed Director of Interventional Cardiovascular Research and Clinical Trials, Mount Sinai Hospital
• Development of a global cardiovascular data and clinical coordination centre
• Assumption of senior leadership roles in major cardiovascular societies and journals
• Appointment as Chief Scientific Officer, Clinical Trials Center, Cardiovascular Research Foundation

Recognition

Professor Mehran is widely regarded as a leading authority in interventional cardiology and cardiovascular clinical trials. Her work has significantly influenced contemporary practice in antithrombotic therapy and trial design, particularly in the context of complex coronary and structural heart interventions. She is frequently invited to speak at major international cardiology meetings and is recognised for her leadership in advancing sex-specific cardiovascular research and mentoring the next generation of clinician-scientists.

Areas of Speciality

• Interventional Cardiology
• Cardiovascular Clinical Trials
• Anticoagulation and Antiplatelet Therapy
• Angioplasty and Transcatheter Valve Procedures
• Sex-Specific Cardiovascular Outcomes
• Population Health in Cardiology

Sources

• https://icahn.mssm.edu/profiles/roxana-mehran
• https://www.mountsinai.org/care/heart
• https://www.jacc.org
• https://www.ahajournals.org
• https://scai.org
• https://www.crf.org
• https://www.radcliffecardiology.com/journal/interventional-cardiology