Skip to main content
  • Home
  •  Prof Nicolas Van Mieghem

Nicolas M Van Mieghem

Medical Director

Thoraxcenter, Erasmus University Medical Center, Rotterdam, NL

Biography

Prof Nicolas Maria Van Mieghem is an Interventional cardiologist at Thoraxcenter, Erasmus MC, Rotterdam, NL decided to pursue a career that would help others. “I enjoy the feeling of being able to help someone or do something important for them". His father was a general cardiologist and one of his biggest influences early in his career.

Prof Van Mieghem initially intended to train as a cardiac surgeon but decided to specialise in interventional cardiology instead, following advice from a mentor. This decision was cemented when he read the first-in-human case report of transcatheter aortic valve implantation (TAVI) in Circulation by Alain Cribier in 2002. Prof Van Mieghem believes that great cardiologist genuinely cares for their patients. He names Gary Roubin, Dr Manu Malbrain and Professor Patrick Serruys among his mentors. 

His current research focuses on cerebral embolic protection during TAVI and the search for improved large bore closure devices. He works actively in expanding TAVI indications, most notably TAVI as a means to further unload the left ventricle in heart failure patients with moderate aortic stenosis (the TAVR UNLOAD trial). Prof Van Mieghem is also involved in the development and dispersion of mechanical circulatory support (MCS) devices as well as transcatheter mitral and tricuspid repair techniques. In terms of imaging and preprocedural planning, his research has covered computed tomography (CT)-derived 3D modelling and printing.

As well as his involvement in percutaneous coronary interventions and structural heart programs, he has published and co-authored over 350 scientific papers in peer-reviewed journals. Professor Van Mieghem is a principal investigator and steering committee member in multiple ongoing international trials, evaluating various coronary and transcatheter valve technologies. He is a Fellow of the European Society of Cardiology (FESC) and is currently Medical Director of the department of Interventional cardiology at the Thorax Centre.

 Prof Van Mieghem is on the ICR3 Editorial Board.

 

Featured Courses

TIO 2023 – Debates
  • 1.00 EBAC

Learning objectives

  • Compare the utility of repair and replacement valve technology in mitral regurgitation
  • Individualise valve choice for aortic regurgitation based on valve durability and patient features
  • Recall the utility and limitations of specialty balloons
  • Evaluate emerging approaches to the treatment of complex left main and other coronary bifurcation lesions
  • Discuss the impact of PCI on top of optimal medical therapy in ischaemic left ventricular systolic dysfunction
  • Identify suitable patients for interatrial shunting
  • Discuss the merits of alternative antiplatelet strategies to DAPT in ACS and CCS following PCI
See more
TIO 2023 – Debates & Controversies – Live Cases & Discussions
  • 1.00 EBAC

Learning objectives

  • Compare the utility of repair and replacement valve technology in mitral regurgitation
  • Individualise valve choice for aortic regurgitation based on valve durability and patient features
  • Recall the utility and limitations of specialty balloons
  • Evaluate emerging approaches to the treatment of complex left main and other coronary bifurcation lesions
  • Discuss the impact of PCI on top of optimal medical therapy in ischaemic left ventricular systolic dysfunction
  • Identify suitable patients for interatrial shunting
See more
TIO 2023 – Keynote & Debate
  • 1.00 EBAC

Learning objectives

  • Compare the utility of repair and replacement valve technology in mitral regurgitation
  • Individualise valve choice for aortic regurgitation based on valve durability and patient features
  • Recall the utility and limitations of specialty balloons
  • Evaluate emerging approaches to the treatment of complex left main and other coronary bifurcation lesions
  • Discuss the impact of PCI on top of optimal medical therapy in ischaemic left ventricular systolic dysfunction
  • Identify suitable patients for interatrial shunting
See more
TIO 2023 – Balloon Revolution – Live Cases & Discussions
  • 1.00 EBAC

Learning objectives

  • Compare the utility of repair and replacement valve technology in mitral regurgitation
  • Individualise valve choice for aortic regurgitation based on valve durability and patient features
  • Recall the utility and limitations of specialty balloons
  • Evaluate emerging approaches to the treatment of complex left main and other coronary bifurcation lesions
  • Discuss the impact of PCI on top of optimal medical therapy in ischaemic left ventricular systolic dysfunction
  • Identify suitable patients for interatrial shunting
  • Discuss the merits of alternative antiplatelet strategies to DAPT in ACS and CCS following PCI
See more
TIO 2023 – Balloon Revolution
  • 1.00 EBAC

Learning objectives

  • Compare the utility of repair and replacement valve technology in mitral regurgitation
  • Individualise valve choice for aortic regurgitation based on valve durability and patient features
  • Recall the utility and limitations of specialty balloons
  • Evaluate emerging approaches to the treatment of complex left main and other coronary bifurcation lesions
  • Discuss the impact of PCI on top of optimal medical therapy in ischaemic left ventricular systolic dysfunction
  • Identify suitable patients for interatrial shunting
  • Discuss the merits of alternative antiplatelet strategies to DAPT in ACS and CCS following PCI
See more
TIO 2023 – Key Issues in TAVI - Live Cases and Discussions
  • 1.00 EBAC

Learning objectives

  • Compare the utility of repair and replacement valve technology in mitral regurgitation
  • Individualise valve choice for aortic regurgitation based on valve durability and patient features
  • Recall the utility and limitations of specialty balloons
  • Evaluate emerging approaches to the treatment of complex left main and other coronary bifurcation lesions
  • Discuss the impact of PCI on top of optimal medical therapy in ischaemic left ventricular systolic dysfunction
  • Identify suitable patients for interatrial shunting
  • Discuss the merits of alternative antiplatelet strategies to DAPT in ACS and CCS following PCI
See more
TIO 2022 - Session 3.4: Debates
  • 1.00 EBAC

Learning objectives

  • Describe the practical implications of TAVI in the context of coronary artery disease, atrioventricular valve disease and transcatheter heart valve degeneration
  • Select appropriate tools for calcified coronary artery disease, including mechanical circulatory support and invasive imaging techniques
  • Understand coronary physiology, novel recanalization and goal-oriented planning for chronic total occlusion
  • Evaluate the role of novel oral anticoagulants in transcatheter aortic valve implantation
  • Discuss the need for gender-specific trials and renal denervation
See more
TIO 2022 - Session 3.3: Keynote & Controversies: Live Cases And Discussion
  • 1.00 EBAC

Learning objectives

  • Describe the practical implications of TAVI in the context of coronary artery disease, atrioventricular valve disease and transcatheter heart valve degeneration
  • Select appropriate tools for calcified coronary artery disease, including mechanical circulatory support and invasive imaging techniques
  • Understand coronary physiology, novel recanalization and goal-oriented planning for chronic total occlusion
  • Evaluate the role of novel oral anticoagulants in transcatheter aortic valve implantation
  • Discuss the need for gender-specific trials and renal denervation
See more
TIO 2022 - Session 2.4 Practical Pearls Toward a More Advanced CTO Programme: Live Cases and Discussion
  • 1.00 EBAC

Learning objectives

  • Describe the practical implications of TAVI in the context of coronary artery disease, atrioventricular valve disease and transcatheter heart valve degeneration
  • Select appropriate tools for calcified coronary artery disease, including mechanical circulatory support and invasive imaging techniques
  • Understand coronary physiology, novel recanalization and goal-oriented planning for chronic total occlusion
  • Evaluate the role of novel oral anticoagulants in transcatheter aortic valve implantation
  • Discuss the need for gender-specific trials and renal denervation
See more
TIO 2022 - Session 2.3: Practical Pearls Toward a More Advanced CTO Programme
  • 1.00 EBAC

Learning objectives

  • Describe the practical implications of TAVI in the context of coronary artery disease, atrioventricular valve disease and transcatheter heart valve degeneration
  • Select appropriate tools for calcified coronary artery disease, including mechanical circulatory support and invasive imaging techniques
  • Understand coronary physiology, novel recanalization and goal-oriented planning for chronic total occlusion
  • Evaluate the role of novel oral anticoagulants in transcatheter aortic valve implantation
  • Discuss the need for gender-specific trials and renal denervation
See more